| MITE0000001 |
|
AviG2 |
Methylation |
O-methyltransferase |
Streptomyces viridochromogenes Tue57 |
AviG2 is responsible for methylation of the hydroxyl group at position 6... |
| MITE0000002 |
|
AviG4 |
Methylation |
O-methyltransferase |
Streptomyces viridochromogenes Tue57 |
O-methyltransferase and is responsible for methylation of the phenolic h... |
| MITE0000003 |
|
AviG6 |
Methylation |
O-methyltransferase |
Streptomyces viridochromogenes Tue57 |
AviG6 for methylation of the hydroxyl group at position 2 of the D-manno... |
| MITE0000004 |
|
AviG5 |
Methylation |
O-methyltransferase |
Streptomyces viridochromogenes Tue57 |
methylation of the hydroxyl group at position 4 of the D-fucose moiety |
| MITE0000005 |
|
CalO3 |
Halogenation |
Flavin-dependent halogenase |
Micromonospora echinospora |
Iodination of orsellenic acid derivate, assumed to be bound to coenzyme ... |
| MITE0000006 |
|
CalO6 |
Methylation |
O-methyltransferase |
Micromonospora echinospora |
O-methylation of orsellenic acid, assumed to be bound to coenzyme A cofactor |
| MITE0000007 |
|
CalO1 |
Methylation |
O-methyltransferase |
Micromonospora echinospora |
O-methylation of iodinated orsellenic acid derivate, assumed to be bound... |
| MITE0000008 |
|
CalO2 |
Hydroxylation |
Cytochrome P450me |
Micromonospora echinospora |
Hydroxylation of iodinated orsellenic acid derivate, assumed to be bound... |
| MITE0000009 |
|
MeiD |
Methylation |
O-methyltransferase |
Streptomyces nanchangensis |
No description available |
| MITE0000010 |
|
MeiE |
Heterocyclization|Hydroxylation |
Cytochrome P450 |
Streptomyces nanchangensis |
No description available |
| MITE0000011 |
|
MpaG |
Methylation |
O-methyltransferase |
Penicillium brevicompactum |
Catalyzes the O-methylation of demethylmycophenolic acid into mycophenolic acid |
| MITE0000012 |
|
GrhO5 |
Monooxygenation |
Flavoprotein monooxygenase |
Streptomyces sp. JP95 |
No description available |
| MITE0000013 |
|
GrhO6 |
Monooxygenation |
Flavoprotein monooxygenase |
Streptomyces sp. JP95 |
No description available |
| MITE0000014 |
|
MtmMI |
Methylation |
O-methyltransferase |
Streptomyces argillaceus |
4-DPMC is the first stable intermediate of the mithramycin biosynthesis.... |
| MITE0000015 |
|
MtmMII |
Methylation |
C-methyltransferase |
Streptomyces argillaceus |
No description available |
| MITE0000016 |
|
MtmOIV |
Decarboxylation|Oxidation |
Oxygenase |
Streptomyces argillaceus |
No description available |
| MITE0000017 |
|
MtmW |
Reduction |
ketoreductase |
Streptomyces argillaceus |
No description available |
| MITE0000018 |
|
MtmGIV |
Glycosylation |
glycosyltransferase |
Streptomyces argillaceus |
No description available |
| MITE0000019 |
|
MtmGIII |
Glycosylation |
glycosyltransferase |
Streptomyces argillaceus |
No description available |
| MITE0000020 |
|
MtmGII |
Glycosylation |
glycosyltransferase |
Streptomyces argillaceus |
No description available |
| MITE0000021 |
|
SsfM2 |
Methylation |
O-methyltransferase |
Streptomyces sp. SF2575 |
No description available |
| MITE0000022 |
|
SsfM4 |
Methylation |
C-methyltransferase |
Streptomyces sp. SF2575 |
SsfM4 catalyzes C6-methylation |
| MITE0000023 |
|
SsfM1 |
Methylation |
O-methyltransferase |
Streptomyces sp. SF2575 |
No description available |
| MITE0000024 |
|
XanH |
Halogenation |
FAD Halogenase |
Streptomyces flavogriseus |
No description available |
| MITE0000025 |
|
OxyB |
Cyclization |
Cytochrome P450 monooxygenase |
Amycolatopsis orientalis HCCB10007 |
Introduces the first crosslink (biaryl ether) between hpg4 and bht6 of t... |
| MITE0000026 |
|
OxyA |
Cyclization |
Cytochrome P450 monooxygenase. |
Amycolatopsis orientalis HCCB10007 |
Introduces the second crosslink (biaryl ether). |
| MITE0000027 |
|
OxyC |
Cyclization |
Cytochrome P450 monooxygenase |
Amycolatopsis orientalis HCCB10007 |
Installs a biaryl ether bond on the balhiycin precursor. The reaction mi... |
| MITE0000028 |
|
BhaA |
Halogenation |
Halogenase |
Amycolatopsis balhimycina DSM 5908 |
The halogenase chlorinates the second bht residue of the balhimycin prec... |
| MITE0000029 |
|
KtzQ |
Halogenation |
Flavin-dependent halogenase |
Kutzneria sp. 744 |
KtzQ is a regiospecific halogenase that catalyzes the chlorination of L-... |
| MITE0000030 |
|
KtzR |
Halogenation |
Flavin-dependent halogenase |
Kutzneria sp. 744 |
KtzR is a regiospecific halogenase that catalyzes chlorination at the 6-... |
| MITE0000031 |
|
SacF |
Methylation |
SAM-dependent methyltransferase |
Pseudomonas fluorescens |
No description available |
| MITE0000032 |
|
SfmM2 |
Methylation |
SAM-dependent C-methyltransferase |
Streptomyces lavendulae |
Mediates the methylation of tyrosine into 3-methyl-L-tyrosine (3-Me-Tyr)... |
| MITE0000033 |
|
GtfB |
Glycosylation |
Glycosyltransferase |
Actinoplanes teichomyceticus |
Adds N-acetylglucosamine or N-acylglucosamine to Hpg4 of the teicoplanin... |
| MITE0000034 |
|
GtfA |
Glycosylation |
Glycosyltransferase |
Actinoplanes teichomyceticus |
Glycosyltransferase adds N-acetylglucosamine to Bht6 of the teicoplanin... |
| MITE0000035 |
|
Tcp24 a.k.a Orf2* a.k.a. tAtf |
Acylation|Hydrolysis |
Acyltransferase |
Actinoplanes teichomyceticus |
Deacetylates N-acetylglucosaminyl residue on Hpg4 of the teicoplanin precursor. |
| MITE0000036 |
|
tAtf |
Acylation |
Acyltransferase |
Actinoplanes teichomyceticus |
Deacetylates N-acetylglucosaminyl residue on Hpg4 of the teicoplanin precursor. |
| MITE0000037 |
|
GtfE |
Glycosylation |
Glycosyltransferase |
Amycolatopsis orientalis HCCB10007 |
Transfers glucose onto hpg4 in the vancomycin and teicoplanin aglycone. |
| MITE0000038 |
|
OxyA |
Cyclization|Oxidation |
Cytochrome P450 Monooxygenase |
Amycolatopsis orientalis HCCB10007 |
Introduces the second biaryl-ether crosslink between bht2 and hpg4 in th... |
| MITE0000039 |
|
Vmt |
Methylation |
Methyltransferase |
Amycolatopsis orientalis HCCB10007 |
Methylates the N-terminus of the vancomycin backbone. Substrate specific... |
| MITE0000040 |
|
VhaA |
Halogenation |
Flavin-dependent halogenase |
Amycolatopsis orientalis HCCB10007 |
Chlorinates bht 2 and bht 6 of vancomycin. The bond to the PCP domain of... |
| MITE0000041 |
|
OxyB |
Cyclization|Oxidation |
Cytochrome P450 Monooxygenase |
Amycolatopsis orientalis HCCB10007 |
Introduces the first biaryl-ether crosslink between hpg4 and bht6 in the... |
| MITE0000042 |
|
GtfD |
Glycosylation |
Glycosyltransferase |
Amycolatopsis orientalis HCCB10007 |
Transfers vancosamine onto glucose on hpg4 of vancomycin pseudoaglycone. |
| MITE0000043 |
|
SgvP |
Heterocyclization |
cytochrome P450 |
Streptomyces griseoviridis |
No description available |
| MITE0000044 |
|
BotCYP |
Decarboxylation|Oxidation |
Cytochrome P450 |
Streptomyces sp. BC16019 |
P450-catalyzed oxidative decarboxylation of terminal thiazoline of bottr... |
| MITE0000045 |
|
BotOMT |
Methylation |
Carboxyl methyltransferase |
Streptomyces sp. BC16019 |
O-methylating SAM-dependent carboxyl methyltransferase from Streptomyces... |
| MITE0000046 |
|
BotRMT2 |
Methylation |
radical SAM methyltransferase |
Streptomyces sp. BC16019 |
Bottromycin-precursor acting rSAM methyltransferase from Streptomyces sp... |
| MITE0000047 |
|
BotRMT3 |
Methylation |
radical SAM methyltransferase |
Streptomyces sp. BC16019 |
Bottromycin-precursor acting rSAM methyltransferase from Streptomyces sp... |
| MITE0000048 |
|
BotP |
Hydrolysis |
Peptidase |
Streptomyces sp. BC16019 |
Cleavage of N-terminal Met from a NH2-Met-Gly-Pro-Xn chain, exposing a N... |
| MITE0000049 |
|
BotRMT1 |
Methylation |
rSAM methyltransferase |
Streptomyces sp. BC16019 |
Catalysis of radical C-methylation of Phe6 of bottromycin-precursor afte... |
| MITE0000050 |
|
BotAH |
Hydrolysis |
Aminohydrolase |
Streptomyces sp. BC16019 |
Cleaves modified bottromycin precursor peptide between thiazole8 and Met9. |
| MITE0000051 |
|
BotH |
Epimerization |
Epimerase |
Streptomyces sp. BC16019 |
epimerization of L-Asp7 to D-Asp7 of modified bottromycin precursor peptide |
| MITE0000052 |
|
BotC |
Heterocyclization |
Thiazole heterocyclisation-catalyzing YacO protein |
Streptomyces sp. BC16019 |
thiazole heterocyclisation of Cys8 of bottromycin-precursor |
| MITE0000053 |
|
BotCD |
Cyclization |
Macroamidine linkage-catalyzing YacO protein from Streptomyces sp. BC16019 |
Streptomyces sp. BC16019 |
macroamidine macrocyclization of Gly1 and Val4 of bottromycin-precursor |
| MITE0000054 |
|
MibH |
Halogenation |
Flavin-dependent halogenase |
Microbispora corallina |
Flavin-dependent tryptophan-5-halogenase catalyzed halogenation reaction... |
| MITE0000055 |
|
McjC |
Macrolactam formation |
Lassopeptide ATP-dependent lactam synthetase (C-protein, asparagine synt... |
Escherichia coli |
Lassopeptide macrolactam formation after N-terminal cleavage: NH2-G-G-X-... |
| MITE0000056 |
|
McjB |
Hydrolysis |
ATP-dependent protease (cysteine protease-like) |
Escherichia coli |
ATP-dependent N-terminal cleavage of leader peptide, resulting in immatu... |
| MITE0000057 |
|
PntE |
Oxidation |
Baeyer-Villiger monooxygenase |
Streptomyces arenae |
Catalyzes the flavin-dependent Baeyer-Villiger oxidation in the biosynth... |
| MITE0000058 |
|
PntD |
Dehydration|Oxidation |
Non-Heme Iron-Dependent Dehydrogenase/Oxygenase |
Streptomyces arenae |
No description available |
| MITE0000059 |
|
PntM |
Other |
Cytochrome P450 |
Streptomyces arenae |
Catalyzes oxidative rearrangement of final step in pentalenolactone pathway |
| MITE0000060 |
|
PntI |
Oxidation |
Cytochrome P450 |
Streptomyces arenae |
Carboxylation of intermediate in pentalenolactone biosynthetic pathway |
| MITE0000061 |
|
CotB3 |
Hydroxylation |
Cytochrome P450 |
Streptomyces melanosporofaciens |
No description available |
| MITE0000062 |
|
CotB4 |
Hydroxylation |
Cytochrome P450 |
Streptomyces melanosporofaciens |
No description available |
| MITE0000063 |
|
PtlD |
Dehydration|Oxidation |
Non-Heme Iron-Dependent Dehydrogenase/Oxygenase |
Streptomyces avermitilis MA-4680 = NBRC 14893 |
No description available |
| MITE0000064 |
|
PtlI |
Oxidation |
Cytochrome P450 |
Streptomyces avermitilis MA-4680 = NBRC 14893 |
Catalyzes oxidation of pentalen-13-al in the neopentalenolactone pathway |
| MITE0000065 |
|
PtlE |
Oxidation |
Baeyer-Villiger monooxygenase |
Streptomyces avermitilis MA-4680 = NBRC 14893 |
Catalyzes the flavin-dependent Baeyer-Villiger oxidation in the biosynth... |
| MITE0000066 |
|
RebP |
Oxidation |
Cytochrome P-450 |
Lentzea aerocolonigenes |
No description available |
| MITE0000067 |
|
RebD |
Oxidation |
Dichlorochromopyrrolate synthase |
Lentzea aerocolonigenes |
No description available |
| MITE0000068 |
|
RebO |
Oxidation |
Flavin-dependent L-tryptophan oxidase |
Lentzea aerocolonigenes |
No description available |
| MITE0000069 |
|
RebH |
Halogenation |
tryptophane halogenase |
Lentzea aerocolonigenes |
No description available |
| MITE0000070 |
|
RebC |
Oxidation |
Putative FAD-monooxygenase |
Lentzea aerocolonigenes |
FAD-dependent enzyme RebC catalyse the oxidation of two carboxylic acids... |
| MITE0000071 |
|
Bmp2 |
Halogenation |
Flavin-dependent halogenase |
Pseudoalteromonas phenolica O-BC30 |
No description available |
| MITE0000072 |
|
TdaE |
Dioxygenation |
Flavoprotein dioxygenase |
Phaeobacter inhibens DSM 17395 |
TdaE relies on its substrate as electron donor (rather than NAD(P)H) for... |
| MITE0000073 |
|
ClmAH |
Hydrolysis |
Amidohydrolase |
Streptomyces sp. CS40 |
removal of the leucine residue |
| MITE0000074 |
|
ClmM1 |
Methylation |
S-methyltransferase |
Streptomyces sp. CS40 |
No description available |
| MITE0000075 |
|
ClmM2 |
Methylation |
O-methyltransferase |
Streptomyces sp. CS40 |
O-methylation of collismycin D |
| MITE0000076 |
|
JamD |
Halogenation |
Flavin-dependent halogenase |
Lyngbya majuscula |
Flavin-dependent bromination of terminal alkyne |
| MITE0000077 |
|
MdpB1 |
Methylation |
C-methyltransferase |
Actinomadura madurae |
C-methylation of methylsalicylic acid bound to coenzyme A. Auxiliary enz... |
| MITE0000078 |
|
MdpB2 |
Other |
CoA ligase |
Actinomadura madurae |
No description available |
| MITE0000079 |
|
PokM3 |
Other |
CoA ligase |
Streptomyces diastatochromogenes |
No description available |
| MITE0000080 |
|
PokMT1 |
Methylation |
C-methyltransferase |
Streptomyces diastatochromogenes |
C-methylation of methylsalicylic acid bound to coenzyme A. Auxiliary enz... |
| MITE0000081 |
|
AgqB |
Hydroxylation |
alkylresorcinol monooxygenase |
Actinoplanes missouriensis 431 |
No description available |
| MITE0000082 |
|
AgqC |
Methylation |
alkylhydroxyhydroquinone methyltransferase |
Actinoplanes missouriensis 431 |
No description available |
| MITE0000083 |
|
AgqD |
Prenylation |
UbiA-like prenyltransferase |
Actinoplanes missouriensis 431 |
No description available |
| MITE0000084 |
|
NapB2 |
Oxidation |
Monooxygenase |
Streptomyces aculeolatus |
Oxidation of 1,3,6,8-tetrahydroxynaphthalene (THN) to flaviolin. |
| MITE0000085 |
|
NapB5 |
Methylation |
putative methyltransferase |
Streptomyces aculeolatus |
No description available |
| MITE0000086 |
|
NapH1 |
Halogenation|Heterocyclization |
Vanadium-Dependent Chloroperoxidase |
Streptomyces aculeolatus |
No description available |
| MITE0000087 |
|
RslO4 |
Monooxygenation |
Monooxygenase |
Streptomyces bottropensis |
RslO4 catalyzes the monooxygenation of an intermediate in the rishirilid... |
| MITE0000088 |
|
TlmF |
Oxidation |
cytochrome P450 |
Salinispora pacifica DSM 45543 = CNS-863 |
No description available |
| MITE0000089 |
|
CPT2 |
Prenylation |
Nerylneryl diphosphate synthase |
Solanum lycopersicum |
No description available |
| MITE0000090 |
|
TPS21 |
Cyclization |
Terpene cyclase |
Solanum lycopersicum |
Cyclization of nerylneryl diphosphate to form lycosantalene |
| MITE0000091 |
|
CYP71BN1 |
Oxidation |
Cytochrome P450 monooxygenase |
Solanum lycopersicum |
CYP71BN1 catalyzes the two-step oxidation of lycosantalene to lycosantalonol |
| MITE0000092 |
|
BorH |
Halogenation |
Flavin-dependent halogenase |
uncultured bacterium |
Tryptophan-6 halogenation |
| MITE0000093 |
|
PhmJ |
Halogenation |
FAD-dependent halogenase |
Leptolyngbya sp. ISBN3-Nov-94-8 |
PhmJ forms the vinyl bromination in phormidolide A |
| MITE0000094 |
|
TnmK2 |
Dioxygenation |
Iterative cofactorless dioxygenase |
Streptomyces sp. CB03234 |
No description available |
| MITE0000095 |
|
TnmK1 |
Cyclization |
Hydrolase. |
Streptomyces sp. CB03234 |
Catalyzes D-ring-forming Michael addition |
| MITE0000096 |
|
TnmJ |
Dioxygenation |
Cofactorless oxygenase |
Streptomyces sp. CB03234 |
No description available |
| MITE0000097 |
|
PumI |
Oxidation |
Oxidoreductase |
Streptomyces sp. |
No description available |
| MITE0000098 |
|
PumK |
Other |
Carboxylate-Amine Ligase |
Streptomyces sp. |
No description available |
| MITE0000099 |
|
PumJ |
Other |
Pseudouridine synthase |
Streptomyces sp. |
No description available |
| MITE0000100 |
|
PumG |
Amination |
Aminotransferase |
Streptomyces sp. |
No description available |
| MITE0000101 |
|
Cxm5 |
Heterocyclization |
Cytochrome P450 |
Actinoplanes tsinanensis |
No description available |
| MITE0000102 |
|
TrlE |
Other |
Flavoprotein monooxygenase |
Streptomyces cyaneofuscatus |
Combines hydroxylation, decarboxylation and oxidation to generate tropol... |
| MITE0000103 |
|
TrlF |
Other |
decarboxylase, hydrolase |
Streptomyces cyaneofuscatus |
Cleaves off CoA from 2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA |
| MITE0000104 |
|
TrlC |
Hydroxylation |
Oxygenase component of flavoprotein monooxygenase TrlCD |
Streptomyces cyaneofuscatus |
Catalyzes hydroxylation from 7-hydroxytropolone to 3,7-dihydroxytropolone |
| MITE0000105 |
|
GnmP |
Methylation |
Persulfide methyltransferase |
Streptomyces sp. CB01883 |
No description available |
| MITE0000106 |
|
MstE |
Cyclization |
terpene cyclase |
Scytonema sp. PCC 10023 |
No description available |
| MITE0000107 |
|
Mca |
Hydrolysis |
amidase |
Streptomyces cyslabdanicus |
No description available |
| MITE0000108 |
|
CldC |
Oxidation |
Cytochrome P450 |
Streptomyces cyslabdanicus |
No description available |
| MITE0000109 |
|
CmxA |
Cyclization|Deamination |
L-lysine cyclodeaminase |
Myxococcus sp. |
cyclization and deamination of lysine to pipecolic acid |
| MITE0000110 |
|
NgnN4 |
Other |
Proline adenyltransferase |
Nocardia argentinensis |
NgnN4 is responsible for attaching a pyrrole-moiety. |
| MITE0000111 |
|
NgnO3 |
Other|Oxidation |
Dioxygenase |
Nocardia argentinensis |
NgnO3 catalyzes the formation of the ether bridge moiety at position C8/... |
| MITE0000112 |
|
Ngnp1 |
Hydroxylation|Oxidation |
Cytochrome P450 |
Nocardia argentinensis |
Hydroxylation at c-2 |
| MITE0000113 |
|
NgnD |
Cyclization |
Nuclear transport factor 2 family protein |
Nocardia argentinensis |
[6+4] cycloaddition; NgnD acts likely similar to a bispericyclase |
| MITE0000114 |
|
NgnM |
Methylation |
Methyltransferase |
Nocardia argentinensis |
NgnM methylates the hydroxyl group at the 2-position of the macrolactone... |
| MITE0000115 |
|
NgnP2 |
Hydroxylation|Monooxygenation|Oxidation |
Cytochrome P450 |
Nocardia argentinensis |
Hydroxylation at C-18 |
| MITE0000116 |
|
StoC |
Dehydration |
NADH:flavin oxidoreductase |
Pseudomonas fluorescens |
Dehydration; elimination of primary alcohol under formation exo-methylene group |
| MITE0000117 |
|
StoR |
Reduction |
NAD(P)H-dependent oxidoreductase |
Pseudomonas fluorescens |
NADPH dependent reduction of exo-methylene in styrolide B to methyl grou... |
| MITE0000118 |
|
AcaR |
Reduction |
NADPH-dependent oxidoreductase |
Pseudomonas jessenii |
reduction of exocxclic double bond in dehydroacaterin to acaterin |
| MITE0000119 |
|
ScyL2 |
Hydroxylation |
AsaB-like alphaKGDD |
Scytalidium album |
No description available |
| MITE0000120 |
|
ZopL9 a.k.a. ZopK |
Hydroxylation|Ring contraction |
AsaB-like alphaKGDD |
Diffractella curvata |
Catalyzes a ring contraction of the nine-membered central ring to yield ... |
| MITE0000121 |
|
AbmB |
Hydroxylation |
L-Ornithine N(5)-oxygenase |
Streptomyces sp. ATCC 700974 |
N-hydroxylation of delta-amine of ornithin |
| MITE0000122 |
|
AbmA |
Acetylation |
Acetyltransferase |
Streptomyces sp. ATCC 700974 |
No description available |
| MITE0000123 |
|
JuiM |
Acetylation |
Acetyltransferase |
Streptomyces sampsonii |
No description available |
| MITE0000124 |
|
JuiL |
Reduction |
F420-dependent oxidoreductase |
Streptomyces sampsonii |
No description available |
| MITE0000125 |
|
JuiL |
Biaryl bond formation |
Cytochrome P450 |
Streptomyces sampsonii |
No description available |
| MITE0000126 |
|
AetF |
Halogenation |
Flavin-dependent halogenase |
Aetokthonos hydrillicola Thurmond2011 |
Bromination of L-tryptophan, leading to 5-bromotryptophan |
| MITE0000127 |
|
AetA |
Halogenation |
Flavin-dependent halogenase |
Aetokthonos hydrillicola Thurmond2011 |
Bromination of 5-bromoindole, leading to 3,5-tribromoindole |
| MITE0000128 |
|
OrfA |
Halogenation |
Halogenase |
Streptomyces tumemacerans |
FADH2-dependent halogenase in the biosynthesis of chloroalbofungin |
| MITE0000129 |
|
ThnJ |
Deamination |
Aminotransferase |
Streptomyces sp. FXJ1.172 |
No description available |
| MITE0000130 |
|
ThnH |
Halogenation |
tryptophan 6-halogenase |
Streptomyces sp. FXJ1.172 |
chlorinates tryptophan to form 6-Cl-tryptophan (6-Cl-Trp) |
| MITE0000131 |
|
ThnA |
Amination |
amidotransferase |
Streptomyces sp. FXJ1.172 |
No description available |
| MITE0000132 |
|
THAA2 |
Acetylation |
Acetyltransferase |
Arabidopsis lyrata subsp. lyrata |
O-acetylation as final step of the thalianin pathway in Arabidopsis thal... |
| MITE0000133 |
|
THAH |
Hydroxylation |
Cytochrome P450 |
Arabidopsis lyrata subsp. lyrata |
Hydroxylates the intermediate in the thalianin pathway in Arabidopsis th... |
| MITE0000134 |
|
THAS |
Cyclization |
Oxidosqualene cyclase |
Arabidopsis lyrata |
Cyclases the intermediate in the thalianin pathway in Arabidopsis thalia... |
| MITE0000135 |
|
THAO |
Hydroxylation |
Cytochrome P450 |
Arabidopsis lyrata subsp. lyrata |
Hydroxylates the intermediate in the thalianin pathway in Arabidopsis th... |
| MITE0000136 |
|
THAA1 |
Acetylation |
Acyltransferase subfamily IIIa, Arabidopsis lyrata ssp lyrata |
Could not resolve organism |
Acetylates the intermediate in the thalianin pathway in Arabidopsis thal... |
| MITE0000137 |
|
AnkG |
Other |
ATP-grasp protein |
Aspergillus thermomutatus |
No description available |
| MITE0000138 |
|
AnkE |
Other |
NRPS independent siderophore synthetase |
Aspergillus thermomutatus |
No description available |
| MITE0000139 |
|
AnkD |
Other |
pyridoxal-phosphate dependent enzyme |
Aspergillus thermomutatus |
No description available |
| MITE0000140 |
|
AnkA |
Other |
cRY tRNA-dependent cyclodipeptide synthase |
Aspergillus thermomutatus |
No description available |
| MITE0000141 |
|
AnkF |
Methylation |
o-methyltransferase |
Aspergillus thermomutatus |
No description available |
| MITE0000142 |
|
AnkC |
Monooxygenation |
FAD-dependent monooxygenase |
Aspergillus thermomutatus |
No description available |
| MITE0000143 |
|
AvaC |
Hydrolysis |
kynurenine formamidase |
Aspergillus versicolor |
No description available |
| MITE0000144 |
|
AvaB |
Monooxygenation |
FAD-dependent monooxygenase |
Aspergillus versicolor |
No description available |
| MITE0000145 |
|
AvaD |
Acetylation |
GNAT family N-acetyltransferase |
Aspergillus versicolor |
No description available |
| MITE0000146 |
|
AvaA |
Other |
cRW tRNA-dependent cyclodipeptide synthase |
Aspergillus versicolor |
No description available |
| MITE0000147 |
|
PeuJ |
Hydroxylation |
FMN-dependent monooxygenase |
Streptomyces peucetius subsp. caesius ATCC 27952 |
No description available |
| MITE0000148 |
|
PtlE |
Oxidation |
Baeyer-Villiger monooxygenase |
Streptomyces avermitilis MA-4680 = NBRC 14893 |
No description available |
| MITE0000149 |
|
MciB |
Biaryl bond formation |
P450 installing crosslink |
Micromonospora citrea |
No description available |
| MITE0000150 |
|
CYP158C1 |
Biaryl bond formation |
Cytochrome P450 |
Streptantibioticus cattleyicolor NRRL 8057 = DSM 46488 |
No description available |
| MITE0000151 |
|
PspC |
Oxidation |
Cytochrome P450 monooxygenase |
Penicillium soppii |
catalyzes three-step oxidations at the C-4 methyl group to carboxylic ac... |
| MITE0000152 |
|
ScnB |
Biaryl bond formation |
Cytochrome P450 |
Streptomyces sp. CNQ-509 |
Installs biaryl crosslink between trp-trp |
| MITE0000153 |
|
SgrB |
Biaryl bond formation |
Cytochrome P450 |
Could not resolve organism |
Installs biaryl crosslink between his-his |
| MITE0000154 |
|
PeuJ |
Hydroxylation |
|
Streptomyces seoulensis |
Monooxygenase |
| MITE0000155 |
|
SrsB |
Methylation |
Methyltransferase |
Streptomyces griseus subsp. griseus NBRC 13350 |
O-methylation of alkylresorcinols to yield alkylresorcinol methyl ethers |
| MITE0000156 |
|
PhoM |
Monooxygenation |
Flavin-dependent monooxygenase |
Diaporthe sp. |
The monooxygenase PhoM is involved in C5 hydroxlation during biosynethes... |
| MITE0000157 |
|
PhoL |
Reduction |
Short-chain dehydrogenases/reductase |
Diaporthe sp. |
PhoL is responsible for reduction of monodictyphenone towards the biosyn... |
| MITE0000158 |
|
PhoJ |
Dioxygenation |
Dioxygenase |
Diaporthe sp. |
PhoJ is a dioxygenase involved in a ring-opening strategy to form monodi... |
| MITE0000159 |
|
PhoD |
Dehydration |
Dehydratase |
Diaporthe sp. |
PhoD is a dehydratase responsible for the formation of the intermediate ... |
| MITE0000160 |
|
PhoC |
Reduction |
Short-chain dehydrogenases/reductase (SDR) |
Diaporthe sp. |
PhoD is a reductase responsible for the reduction of a double bond durin... |
| MITE0000161 |
|
PhoK |
Acetylation|Reduction |
Reductase |
Diaporthe sp. |
No description available |
| MITE0000162 |
|
PhoG |
Oxidation |
Anthrone oxygenase |
Diaporthe sp. |
Responsible for the conversion of emodin anthrone to emodin by oxidation... |
| MITE0000163 |
|
PhoH |
Decarboxylation |
Decarboxylase |
Diaporthe sp. |
Decarboxylase responsible for the conversion of atrochrysone carboxylic ... |
| MITE0000164 |
|
PhoP |
Reduction |
Short-chain dehydrogenases/reductase |
Diaporthe sp. |
PhoP is a short-chain dehydrogenases/reductase responsible for a reducti... |
| MITE0000165 |
|
PhoN |
Other |
Isomerase |
Diaporthe sp. |
No description available |
| MITE0000166 |
|
ProsF |
Methylation |
O-methyltransferase |
Phaeosphaeria sp. |
SAM (S-adenosyl-L-methionine)-depenent O-methylation of roseopurpurin in... |
| MITE0000167 |
|
ProsD |
Hydrolysis |
Glyoxalase |
Phaeosphaeria sp. |
Ring cleavage in the scope of detoxification. |
| MITE0000168 |
|
ProsA |
Oxidation |
Cytochrome P450 |
Phaeosphaeria sp. |
ProsA works in concert with SDR ProsC to yield the pathway intermediate.... |
| MITE0000169 |
|
ProsC |
Reduction |
Short-chain dehydrogenase/reductase |
Phaeosphaeria sp. |
ProsC works in concert with P450 ProsA to yield the pathway intermediate... |
| MITE0000170 |
|
ProsK |
Cyclization |
Cytochrome P450 |
Phaeosphaeria sp. |
Depside bond formation by oxidative ether formation. |
| MITE0000171 |
|
ProsB |
Decarboxylation |
Decarboxylase |
Phaeosphaeria sp. |
Decarboxylates the phenolic substrate |
| MITE0000172 |
|
LauB1 |
Biaryl bond formation |
Cytochrome P450 |
Streptomyces laurentii |
Installs biaryl crosslinks |
| MITE0000173 |
|
ScaB aka EmbB |
Biaryl bond formation |
Cytochrome P450 |
Streptomyces sp. SID5474 |
W-W biaryl crosslink formation |
| MITE0000174 |
|
BytO |
Biaryl bond formation |
cytochrome P450 |
Planomonospora sp. |
Introduces a biaryl bond between Y1 and H3, cytochrome P450 from Planomo... |
| MITE0000175 |
|
BytO |
Biaryl bond formation |
cytochrome P450 |
Planomonospora sp. |
Biaryl formation between Y1 and H3 of the tripeptide, cytochrome P450, P... |
| MITE0000176 |
|
Ple1 |
Hydroxylation |
Cytochrome P450 |
Rhodocybe pseudopiperita |
Hydroxylation, Ple1 catalyzed hydroxylation on the α position of the ace... |
| MITE0000177 |
|
Ple2 |
Acetylation |
Acetyltransferase |
Rhodocybe pseudopiperita |
Acetylation, O-acetylation of mutilin to produce 14-acetyl-mutilin |
| MITE0000178 |
|
Ple6 |
Hydroxylation |
Cytochrome P450 |
Rhodocybe pseudopiperita |
Hydroxylation |
| MITE0000179 |
|
Ple5 |
Hydroxylation |
Cytochrome P450 |
Rhodocybe pseudopiperita |
Hydroxylation |
| MITE0000180 |
|
SLI_0884 |
Other |
Leucyl/Phenylalanil-tRNA-Protein transferase |
Streptomyces lividans 1326 |
amide bond formation between arginine, encoded by the A domain of the NR... |
| MITE0000181 |
|
FrsC |
Reduction |
specialized dehydrogenase for phenyllactate biosynthesis |
Chromobacterium vaccinii |
Reduction of phenylpyruvate to L-phenyllactate |
| MITE0000182 |
|
SxtN |
Sulfonation |
N-sulfotransferase |
Heteroscytonema crispum UCFS15 |
N-sulfonation of saxitoxin |
| MITE0000183 |
|
EryK |
Hydroxylation |
Cytochrome P450 |
Saccharopolyspora erythraea NRRL 2338 |
C-12 hydroxylation of erythromycin B to form erythromycin A |
| MITE0000184 |
|
RufO |
Other |
Cytochrome p450 monooxygenase |
Streptomyces atratus |
direct nitration of tyrosine in MRYLH pentapeptide |
| MITE0000185 |
|
FrsH |
Hydroxylation |
non-heme diiron monooxygenase |
Chromobacterium vaccinii |
beta-hydroxylation of PCP-bound leucine |
| MITE0000186 |
|
HrmF |
Other |
L-DOPA dioxygenase |
Streptomyces griseoflavus |
extradiol cleavage of L-DOPA, rearrangement to alkylproline derivative |
| MITE0000187 |
|
HrmI |
Oxidation |
heme oxygenase-like dinuclear iron enzyme |
Streptomyces griseoflavus |
oxidation of lysine to nitronorleucine |
| MITE0000188 |
|
BorI |
Dehydration|Hydroxylation|Oxidation |
Cytochrome P450 monooxygenase |
Streptomyces parvulus |
Oxidation of 12-C hydroxyl group of pre-borrelidin to a carbonyl |
| MITE0000189 |
|
BorJ |
Amination |
Aminotransferase |
Streptomyces parvulus |
Replaces 12-C carbonyl with primary amine on the pre-borrelidin intermediate |
| MITE0000190 |
|
AurH |
Oxidation |
Cytochrome P450 Monooxygenase |
Streptomyces thioluteus |
Oxidation leads to furan-formation |
| MITE0000191 |
|
PatG |
Decarboxylation |
Decarboxylase |
Penicillium expansum |
Decarboxylation of 6-methylsalicylic in the patulin biosynthetic pathway |
| MITE0000192 |
|
CtoA |
Halogenation |
Halogenase |
Sorangium cellulosum |
Dichlorination of chlorotonil precursor. |
| MITE0000193 |
|
AlbA |
Dehydrogenation |
Albonoursin synthase/cyclic dipeptide oxidase |
Streptomyces noursei ATCC 11455 |
Dehydrogenates cyclo(L-Phe-L-Leu) in the scope of the albonoursin biosyn... |
| MITE0000194 |
|
PhoO |
Biaryl bond formation |
Cytochrome P450 |
Diaporthe sp. |
PhoO dimerizes penexanthone B to phomoxanthone A |
| MITE0000195 |
|
HrmJ |
Other |
alpha-ketoglutarate-dependent dioxygenase |
Streptomyces griseoflavus |
cyclopropanation (nitronorleucine - nitrocyclopropylalanine) |
| MITE0000196 |
|
HynE |
Hydroxylation |
alpha-ketoglutarate-dependent dioxygenase |
Lysobacter sp. K5869 |
beta-hydroxylation of PCP-bound asparagine (anti) |
| MITE0000197 |
|
HynC |
Hydroxylation |
non-heme diiron monooxygenase |
Lysobacter sp. K5869 |
beta-hydroxylation of PCP-bound tyrosine (syn) |
| MITE0000198 |
|
PyrH |
Halogenation |
Flavin-dependent 5-halogenase |
Streptomyces rugosporus |
Chlorinates free-floating L-tryptophan exclusively in position 5 |