Minimum Information about a Tailoring Enzyme Repository

MITE0000176

MITE0000177

MITE0000178

Reaction Information

Number of Known Reactions: 2

Reaction 1

Description	Acetylation, O-acetylation of mutilin to produce 14-acetyl-mutilin
Tailoring	Acetylation
Database References	No database crosslinks available
Evidence	Heterologous expression
References	doi:10.1038/s41467-017-01659-1 doi:10.1002/cbic.201700434

Example 1

Metadata	Description: No description available Intermediate: False
Substrate 1
Product 1

Reaction 2

Description	Acetylation, O-acetylation of 3,11-diol-mutilin to produce 3,11-diol-14-acetyl-mutilin
Tailoring	Acetylation
Database References	No database crosslinks available
Evidence	Heterologous expression
References	doi:10.1039/d2sc06638f

Example 1

Metadata	Description: No description available Intermediate: False
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000177
Entry Status	Status: active
Enzyme Name	Ple2
Enzyme Description	Acetyltransferase
Database References	UniProtKB: A0A6S6QLX9 NCBI GenPept: BCI98770.1 MIBiG: BGC0002181
References	doi:10.1038/s41467-017-01659-1 doi:10.1002/cbic.201700434 doi:10.1038/srep25202 doi:10.1039/d2sc06638f
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-11-14)

Contributor(s)	0000-0001-6585-0696
Reviewer(s)	0000-0003-4819-2251 0000-0002-9747-3423
Comment	"Initial entry. Reviewers checked factual correctness of submission, verified Database ID crosslinks and added where possible. References were properly formatted."