Minimum Information about a Tailoring Enzyme Repository

MITE0000174

MITE0000175

MITE0000176

Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	Biaryl formation between Y1 and H3 of the tripeptide, cytochrome P450, Planomonospora strain ID82291
Tailoring	Biaryl bond formation
Database References	No database crosslinks available
Evidence	Heterologous expression
References	doi:10.1016/j.chembiol.2020.11.009

Example 1

Metadata	Description: Modifies biarylitide YYH precursor MRYYH Intermediate: False
Substrate
Product 1

Enzyme Information

Accession ID	MITE0000175
Entry Status	Status: active
Enzyme Name	BytO
Enzyme Description	cytochrome P450
Database References	UniProtKB: A0A891LWT6 NCBI GenPept: QRM13814.1 MIBiG: BGC0002084
Cofactors	Organic Heme Inorganic Fe
References	doi:10.1016/j.chembiol.2020.11.009
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-11-12)

Contributor(s)	0000-0001-6534-6609
Reviewer(s)	0000-0002-9747-3423
Comment	"Initial entry. Reviewer 1 checked entries, crosslinks, databases and references"

Version 2 (2025-07-25)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609
Comment	"Added cofactor information"