Minimum Information about a Tailoring Enzyme Repository

MITE0000173

MITE0000174

MITE0000175

Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	Introduces a biaryl bond between Y1 and H3, cytochrome P450 from Planomonospora strain ID107089
Tailoring	Biaryl bond formation
Database References	No database crosslinks available
Evidence	Heterologous expression
References	doi:10.1016/j.chembiol.2020.11.009

Example 1

Metadata	Description: Modifies biarylitide YFH precursor MRYFH Intermediate: False
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000174
Entry Status	Status: active
Enzyme Name	BytO
Enzyme Description	Cytochrome P450
Database References	UniProtKB: A0A891LYB2 NCBI GenPept: QRM13816.1 MIBiG: BGC0002099
Cofactors	Organic Heme Inorganic Fe
References	doi:10.1016/j.chembiol.2020.11.009
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-11-12)

Contributor(s)	0000-0001-6534-6609
Reviewer(s)	0000-0002-9747-3423
Comment	"Initial entry. Reviewer 1 checked entries, references and for factual correctness"

Version 2 (2025-07-25)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609
Comment	"Added cofactor information"

Version 3 (2025-08-26)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609
Comment	"Homogenized enzyme descriptions"