MITE0000172

MITE0000173

MITE0000174

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description W-W biaryl crosslink formation
Tailoring
  • Biaryl bond formation
Database References No database crosslinks available
Evidence
  • Heterologous expression
References
Example 1
Metadata
  • Description: Biaryl-bond formation in the scabrirubin precursor peptide TWFIWYS before final cleavage
  • Intermediate: True
Substrate substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000173
Entry StatusStatus: active
Enzyme NameScaB aka EmbB
Enzyme DescriptionCytochrome P450
Database References
Cofactors
  • Organic
    • Heme
  • Inorganic
    • Fe
References
CommentDefining step of scabrirubin biosynthesis
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)
Reviewer(s)
Comment "Initial entry. Reviewer fixed reactionSMARTS:reactionSMARTS."

Version 2 (2025-02-20)

Contributor(s)
Reviewer(s)
Comment "Replaced reference, reworked reaction to take full precursor, replaced enzyme IDs"

Version 3 (2025-07-25)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "Added cofactor information"