Minimum Information about a Tailoring Enzyme Repository

MITE0000096

MITE0000097

MITE0000098

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Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	Dehydrogenates (oxidates) pseudouridine in the pseudouridimycin pathway.
Tailoring	Dehydrogenation
Database References	No database crosslinks available
Evidence	Knock-out studies
References	doi:10.1016/j.chembiol.2018.02.008

Example 1

Metadata	Description: Dehydrogenates pseudouridine to pseudouridine aldehyde. Intermediate: True
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000097
Entry Status	Status: active
Enzyme Name	PumI
Enzyme Description	Oxidoreductase
Database References	UniParc: UPI000D213889 NCBI GenPept: AVT42378.1
References	doi:10.1016/j.chembiol.2018.02.008
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)	0000-0003-1763-2525 0009-0008-3623-3734 Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609 0000-0003-0443-9902
Comment	"Initial entry. Reviewer partially fixed reactions:substrate, validation still not passing. Reviewer partially fixed reactions:products, validation still not passing. Reviewer 2 reworked reaction SMARTS, reaction passes."

Version 2 (2025-10-27)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609
Comment	"Replaced retired UniProtKB ID with UniParc ID"

Version 3 (2026-02-27)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609
Comment	"Added reaction description, changed tailoring term from oxidation to dehydrogenation."