Minimum Information about a Tailoring Enzyme Repository

MITE0000097

MITE0000098

MITE0000099

Modify entry

Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	Transfers glutamine to 5'-aminopseudouridine in pseudouridimycin pathway.
Tailoring	Other
Database References	No database crosslinks available
Evidence	Knock-out studies
References	doi:10.1016/j.chembiol.2018.02.008

Example 1

Metadata	Description: Converts 5'-aminopseudouridine to glutamine-5'-aminopseudouridine Intermediate: True
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000098
Entry Status	Status: active
Enzyme Name	PumK
Enzyme Description	Carboxylate-amine ligase
Database References	UniParc: UPI000D1FFAB8 NCBI GenPept: AVT42380.1
References	doi:10.1016/j.chembiol.2018.02.008
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)	0000-0003-1763-2525 0009-0008-3623-3734 Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609 0000-0003-0443-9902
Comment	"Initial entry. Reviewer partially fixed general aromaticity. Reviewer 2 reworked reaction SMARTS, reaction passes."

Version 2 (2025-08-26)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609
Comment	"Homogenized enzyme descriptions"

Version 3 (2025-10-27)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609
Comment	"Replaced retired UniProtKB ID with UniParc ID"

Version 4 (2026-02-27)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609
Comment	"Added reaction description. Reviewer 1 removed MIBIG ID BGC0001476 (does not exist in MIBiG 4.0)"