MITE0000045

MITE0000046

MITE0000047

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Bottromycin-precursor acting rSAM methyltransferase from Streptomyces sp BC16019;C-methylation of both Val4 and Val5 of bottromycin A2
Tailoring
  • Methylation
Database References No database crosslinks available
Evidence
  • Knock-out studies
References
Example 1
Metadata
  • Description: Bottromycin A2-precursor peptide with cleaved N-terminal Met, first 10 AAs.
  • Intermediate: True
Substrate substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000046
Entry StatusStatus: active
Enzyme NameBotRMT2
Enzyme Descriptionradical SAM methyltransferase
Database References
Cofactors
  • Organic
    • SAM
  • Inorganic
    • FeS
References
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)
Reviewer(s)
Comment "Initial entry. Reviewer partially fixed reactionSMARTS:reactionSMARTS, validation still not passing. Reviewer 2 fixed reaction SMARTS numbering. Reviewer 3 switched text of enzyme description and enzyme reaction description."

Version 2 (2025-07-25)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "Added cofactor information"