MITE0000112

MITE0000113

MITE0000114

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description [6+4] cycloaddition; NgnD acts likely similar to a bispericyclase
Tailoring
  • Cyclization
Database References No database crosslinks available
Evidence
  • Knock-out studies
References
Example 1
Metadata
  • Description: No description available
  • Intermediate: True
Substrate substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000113
Entry StatusStatus: active
Enzyme NameNgnD
Enzyme DescriptionNuclear transport factor 2 family protein
Database References
References
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)
Reviewer(s)
Comment "Initial entry. Reviewer fixed reactionSMARTS:reactionSMARTS. Reviewer 2 checked entry for correctness, changed enzyme and reaction description"

Auxiliary Enzyme #1

Enzyme Name NgnN4
Description NgnN4 is responsible for attaching the pyrrole moiety at hydroxyl group at the 9-position of substrate.
Database References

Auxiliary Enzyme #2

Enzyme Name NgnO3
Description NgnO3 catalyzes the formation of the ether bridge moiety at position C8/C13 of the substrate molecules.
Database References

Auxiliary Enzyme #3

Enzyme Name NgnP2
Description Hydroxylation at c-18
Database References

Auxiliary Enzyme #4

Enzyme Name NgnP1
Description Hydroxylation at c-2
Database References