MITE0000211

MITE0000212

MITE0000213

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Glycosylation of phosphoramidon peptidic intermediate with L-rhamnose
Tailoring
  • Glycosylation
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • In vitro assay
  • Knock-out studies
References
Example 1
Metadata
  • Description: Installation of L-rhamnose on the phosphoramidon peptidic intermediate, leading to phosphoramidon
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000212
Entry StatusStatus: active
Enzyme NameTalC
Enzyme DescriptionDeoxysugar transferase
Database References
References
CommentInvolved in phosphoramidon/talopeptin biosynthesis
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2025-09-25)

Contributor(s)
Reviewer(s)
Comment "New entry. Added TalE as auxiliary enzyme (phosphorylation step is required for glycosylation); corrected "installation of dTDP-L-rhamnose" to "installation of L-rhamnose", since only the sugar moiety is retained, while the dTDP is cleaved off."

Auxiliary Enzyme #1

Enzyme Name TalD
Description ATP grasp enzyme (gatekeeping)
Database References

Auxiliary Enzyme #2

Enzyme Name TalE
Description Kinase
Database References