MITE0000213

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Install an N-terminal phosphoramidate on peptidic substrate
Tailoring
  • Phosphorylation
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • In vitro assay
  • Knock-out studies
References
Example 1
Metadata
  • Description: Phosphorylation of a L-W dideptide
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000213
Entry StatusStatus: active
Enzyme NameTalE
Enzyme DescriptionKinase
Database References
Cofactors
  • Inorganic
    • Mg
References
CommentInvolved in phosphoramidon/talopeptin biosynthesis
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2025-09-25)

Contributor(s)
Reviewer(s)
Comment "New entry. Changed enzyme description to kinase, which is more specific (=enzyme that uses ATP as phosphate donor); added inorganic cofactor Mg."

Auxiliary Enzyme #1

Enzyme Name TalD
Description ATP grasp enzyme (gatekeeping)
Database References