Minimum Information about a Tailoring Enzyme Repository

MITE0000064

MITE0000065

MITE0000066

Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	Catalyzes the flavin-dependent Baeyer-Villiger oxidation in the biosynthesis of neopentalenolactone
Tailoring	Oxidation
Database References	RHEA: 34639 BRENDA: 1.14.13.171 Expasy ENZYME: 1.14.13.171
Evidence	Knock-out studies
References	doi:10.1021/bi1019786

Example 1

Metadata	Description: Converts 1-deoxy-11-oxopentalenic acid to neopentalenolactone D Intermediate: True
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000065
Entry Status	Status: active
Enzyme Name	PtlE
Enzyme Description	Baeyer-Villiger monooxygenase
Database References	UniProtKB: Q82IY8 NCBI GenPept: BAC70705.1 MIBiG: BGC0000678
References	doi:10.1021/bi060419n
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)	0000-0003-3002-6458 Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609
Comment	"Initial entry. Reviwer 1 reworked reaction SMARTS and added descriptions."