Reaction Information
Number of Known Reactions: 2
Reaction 1
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| Description | The halogenase chlorinates the second bht residue of the balhimycin precursor, probably while the precursor is bound to module 6 of the NRPS. The PCP domain of module 6 might be required for the reaction. The substrate specificity of the enzyme might be less specific than represented in the SMARTS pattern. In order to make the specificity not too broad structures were rather kept in the pattern than left out. |
| Tailoring |
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| Database References | No database crosslinks available |
| Evidence |
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| References |
Example 1
| Metadata |
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| Substrate 1 |
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| Product 1 |
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Reaction 2
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| Description | The halogenase chlorinates the bht residue of the balhimycin precursor, probably while the precursor is bound to module 2 of the NRPS. The PCP domain is probably required for the reaction. The substrate specificity of the enzyme might be less specific than represented in the SMARTS pattern. In order to make the specificity not too broad structures were rather kept in the pattern than left out. |
| Tailoring |
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| Database References | No database crosslinks available |
| Evidence |
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| References |
Example 1
| Metadata |
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| Substrate 1 |
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| Product 1 |
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Enzyme Information
| Accession ID | MITE0000028 |
| Entry Status | Status: active |
| Enzyme Name | BhaA |
| Enzyme Description | Halogenase |
| Database References |
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| Cofactors |
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| References | |
| Enzyme Visualization (AlphaFold-predicted) |
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Version 1 (2024-07-30)
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Version 2 (2025-07-25)
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