Minimum Information about a Tailoring Enzyme Repository

MITE0000133

MITE0000134

MITE0000135

Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	Cyclases the intermediate in the thalianin pathway in Arabidopsis thaliana ssp. lyrata
Tailoring	Cyclization
Database References	RHEA: 31035 BRENDA: 4.2.1.124 Expasy ENZYME: 4.2.1.124
Evidence	Heterologous expression
References	doi:10.1038/s41467-020-19153-6

Example 1

Metadata	Description: Cyclizes 2,3-oxidosqualene to thalianol Intermediate: True
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000134
Entry Status	Status: active
Enzyme Name	THAS
Enzyme Description	Oxidosqualene cyclase
Database References	UniParc: UPI000A29AD50 NCBI GenPept: CAH8278777.1 MIBiG: BGC0002857
References	doi:10.1038/s41467-020-19153-6
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609
Comment	"Initial entry. Reviewer 1 fixed reaction SMARTS numbering and database IDs. The original submission specified RefSeq ID XP_020879357.1, which was changed to its GenPept equivalent. Replaced CXSMARTS with normal SMARTS"