MITE0000055

MITE0000056

MITE0000057

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description ATP-dependent N-terminal cleavage of leader peptide, resulting in immature intermediate core peptide.
Tailoring
  • Hydrolysis
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • Site-directed mutagenesis
References
Example 1
Metadata
  • Description: Precursor cleavage of the McjA precursor peptide, resulting in the intermediate core peptide before macrolactam formation.
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000056
Entry StatusStatus: active
Enzyme NameMcjB
Enzyme DescriptionPeptidase
Database References
References
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)
Reviewer(s)
Comment "Initial entry. Reviewer 1 changed text of enzyme description and enzyme reaction description, checked factual correctness and links"

Version 2 (2025-08-26)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "Homogenized enzyme descriptions"

Auxiliary Enzyme #1

Enzyme Name McjC
Description ATP-dependent lactam synthetase
Database References