MITE0000031

MITE0000032

MITE0000033

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Mediates the methylation of tyrosine into 3-methyl-L-tyrosine (3-Me-Tyr) in biosynthesis of saframycin A
Tailoring
  • Methylation
Database References
Evidence
  • In vitro assay
References
Example 1
Metadata
  • Description: No description available
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000032
Entry StatusStatus: active
Enzyme NameSfmM2
Enzyme DescriptionC-methyltransferase
Database References
Cofactors
  • Organic
    • SAM
  • Inorganic
    • FeS
References
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)
Reviewer(s)
Comment "Initial entry. Reviewer 1 fixed numbering of reaction SMARTS, removed explicit charges, and reworked substrate/product."

Version 2 (2025-07-25)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "Added cofactor information"

Version 3 (2025-08-26)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "Homogenized enzyme descriptions. Removed non-covalently bond cofactor from reaction depiction to implement editorial guidelines."