Minimum Information about a Tailoring Enzyme Repository

MITE0000190

MITE0000191

MITE0000192

Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	Decarboxylation of 6-methylsalicylic in the patulin biosynthetic pathway
Tailoring	Decarboxylation
Database References	RHEA: 23112 BRENDA: 4.1.1.52 Expasy ENZYME: 4.1.1.52
Evidence	Heterologous expression In vitro assay
References	doi:10.1016/j.ijfoodmicro.2013.11.020

Example 1

Metadata	Description: Conversion of 6-methylsalicylic acid to m-cresol Intermediate: True
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000191
Entry Status	Status: active
Enzyme Name	PatG
Enzyme Description	Decarboxylase
Database References	UniProtKB: A0A075TXZ1 NCBI GenPept: AIG62133.1 MIBiG: BGC0000120
Cofactors	Inorganic Zn
References	doi:10.1016/j.ijfoodmicro.2013.11.020
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-12-01)

Contributor(s)	0009-0002-2037-5945 0009-0001-9399-9671
Reviewer(s)	0009-0001-3436-5302 0000-0001-6534-6609
Comment	"Initial entry. Reviewer 1 fixed erroneously stated product (patulin) and added reaction databaseId crosslinks."

Version 2 (2025-07-25)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0003-4819-2251
Comment	"Added cofactor information"