MITE0000220

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Hydroxylation of polyene macrolide scaffold to yield ML-449 in Streptomyces isolate MP39-85
Tailoring
  • Hydroxylation
Database References No database crosslinks available
Evidence
  • Inference from genomic data and chemical structure
References
Example 1
Metadata
  • Description: Hydroxylation of polyene macrolide precursor of ML-449
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000220
Entry StatusStatus: active
Enzyme NameMlaO
Enzyme DescriptionHydroxylation
Database References
Cofactors
  • Organic
    • Heme
References
CommentP450 monooxygenase hydroxylating polyene macrolide scaffold
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2025-11-11)

Contributor(s)
Reviewer(s)
Comment "new entry. Reviewer added minor additions to reaction description; cofactor added; and corrected evidence term."