MITE0000043

MITE0000044

MITE0000045

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description P450-catalyzed oxidative decarboxylation of terminal thiazoline of bottromycin precursor in Streptomyces sp. BC16019
Tailoring
  • Decarboxylation
  • Oxidation
Database References No database crosslinks available
Evidence
  • Heterologous expression
References
Example 1
Metadata
  • Description: P450-catalyzed oxidative decarboxylation of terminal thiazoline of bottromycin precursor.
  • Intermediate: True
Substrate substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000044
Entry StatusStatus: active
Enzyme NameBotCYP
Enzyme DescriptionCytochrome P450
Database References
Cofactors
  • Organic
    • Heme
  • Inorganic
    • Fe
References
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)
Reviewer(s)
Comment "Initial entry. Reviewer fixed reaction SMARTS, reaction passes. Reviewer 2 switched text of enzyme description and enzyme reaction description."

Version 2 (2025-07-25)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "Added cofactor information"