Minimum Information about a Tailoring Enzyme Repository

MITE0000089

MITE0000090

MITE0000091

Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	Cyclization of nerylneryl diphosphate to form lycosantalene
Tailoring	Cyclization
Database References	No database crosslinks available
Evidence	Heterologous expression
References	doi:10.1021/ja508477e

Example 1

Metadata	Description: Cyclization of nerylneryl diphosphate to lycosantalene in the first step of the biosynthetic pathway of lycosantalonol Intermediate: True
Substrate
Product 1

Enzyme Information

Accession ID	MITE0000090
Entry Status	Status: active
Enzyme Name	TPS21
Enzyme Description	Terpene cyclase
Database References	UniProtKB: R9R6P6 NCBI GenPept: AGK82800.1 MIBiG: BGC0001322
References	doi:10.1021/ja508477e doi:10.1371/journal.pone.0119302
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0003-4819-2251
Comment	"Initial entry. Reviewer 1 added enzyme type, added reaction descriptions and added appropriate reference where heterologous expression was carried out."