MITE0000049

MITE0000050

MITE0000051

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Cleaves modified bottromycin precursor peptide between thiazole8 and Met9.
Tailoring
  • Hydrolysis
Database References No database crosslinks available
Evidence
  • Heterologous expression
References
Example 1
Metadata
  • Description: bottromycin A2-precursor peptide after methylation, hetero- and macrocyclization. Higher activity of enzyme measured in presence of Cobalt(II).
  • Intermediate: True
Substrate substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000050
Entry StatusStatus: active
Enzyme NameBotAH
Enzyme DescriptionAminohydrolase
Database References
Cofactors
  • Inorganic
    • Zn
References
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)
Reviewer(s)
Comment "Initial entry. Reviewer 1 supplemented description of known reaction to include measured increased enzyme activity in presence of Cobalt(II)."

Version 2 (2025-07-25)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "Added cofactor information"