Minimum Information about a Tailoring Enzyme Repository

MITE0000050

MITE0000051

MITE0000052

Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	epimerization of L-Asp7 to D-Asp7 of modified bottromycin precursor peptide
Tailoring	Epimerization
Database References	No database crosslinks available
Evidence	Heterologous expression
References	doi:10.1038/s41589-020-0624-8

Example 1

Metadata	Description: bottromycin A2 precursor peptide after follower peptide cleavage Intermediate: True
Substrate
Product 1

Enzyme Information

Accession ID	MITE0000051
Entry Status	Status: active
Enzyme Name	BotH
Enzyme Description	Epimerase
Database References	UniProtKB: K4MHV9 NCBI GenPept: AFV25485.1 MIBiG: BGC0000469
References	doi:10.1038/s41589-020-0624-8 doi:10.1039/d0np00097c
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)	0000-0001-6534-6609
Reviewer(s)	0000-0001-6534-6609 0000-0003-0443-9902
Comment	"Initial entry. Reviewer partially fixed reactionSMARTS:reactionSMARTS, validation still not passing. Reviewer partially fixed reactions:substrate, validation still not passing. Reviewer partially fixed reactions:products, validation still not passing. Reviewer 2 reworked numbering of reaction SMARTS, reaction passing."