MITE0000048

MITE0000049

MITE0000050

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Catalysis of radical C-methylation of Phe6 of bottromycin-precursor after precursor Met cleavage.
Tailoring
  • Methylation
Database References No database crosslinks available
Evidence
  • Knock-out studies
References
Example 1
Metadata
  • Description: Bottromycin A2-precursor peptide with cleaved N-terminal Met, first 10 AAs.
  • Intermediate: True
Substrate substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000049
Entry StatusStatus: active
Enzyme NameBotRMT1
Enzyme DescriptionrSAM methyltransferase
Database References
Cofactors
  • Organic
    • SAM
  • Inorganic
    • FeS
References
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)
Reviewer(s)
Comment "Initial entry. Reviewer 1 removed parentheses around reaction SMARTS, reaction passes."

Version 2 (2025-07-25)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "Added cofactor information"