Reaction Information
Number of Known Reactions: 1
Reaction 1
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| Description | TdaE relies on its substrate as electron donor (rather than NAD(P)H) for O2 activation and covalent flavin-oxygen adduct formation. Then, TdaE incorporates both O2-derived oxygen atoms into the substrate most likely via transient FlN5OO and FlN5O species, thereby breaking the CoA thioester bond and epoxidizing the tropone ring. |
| Tailoring |
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| Database References | No database crosslinks available |
| Evidence |
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| References |
Example 1
| Metadata |
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| Substrate 1 |
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| Product 1 |
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Enzyme Information
| Accession ID | MITE0000072 |
| Entry Status | Status: active |
| Enzyme Name | TdaE |
| Enzyme Description | Flavoprotein dioxygenase |
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| Enzyme Visualization (AlphaFold-predicted) |
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Version 1 (2024-07-30)
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