Reaction Information
Number of Known Reactions: 2
Reaction 1
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| Description | Glycosyltransferase adds N-acetylglucosamine to Bht6 of the teicoplanin precursor. Substrate specificity is probably more general than depicted in the reaction SMARTS, but there is no precise information on substrate specificity. In order to avoid making the reaction too general, the complete backbone is included in the pattern. |
| Tailoring |
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| Database References | No database crosslinks available |
| Evidence |
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| References |
Example 1
| Metadata |
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| Substrate |
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| Product 1 |
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Reaction 2
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| Description | Glycosyltransferase adds N-acetylglucosamine to Bht6 of the teicoplanin precursor. Substrate specificity is probably more general than depicted in the reaction SMARTS, but there is no precise information on substrate specificity. In order to avoid making the reaction too general, the complete backbone is included in the pattern. |
| Tailoring |
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| Database References | No database crosslinks available |
| Evidence |
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| References |
Example 1
| Metadata |
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| Substrate |
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| Product 1 |
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Enzyme Information
| Accession ID | MITE0000034 |
| Entry Status | Status: active |
| Enzyme Name | GtfA |
| Enzyme Description | Glycosyltransferase |
| Database References |
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| References | |
| Comment | The enzyme seems to be highly specific for the backbone of teicoplanin, as it does not recognize the closely related vancomycin aglycone. |
| Enzyme Visualization (AlphaFold-predicted) |
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Version 1 (2024-07-30)
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