Minimum Information about a Tailoring Enzyme Repository

MITE0000186

MITE0000187

MITE0000188

Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	oxidation of lysine to nitronorleucine
Tailoring	Oxidation
Database References	No database crosslinks available
Evidence	Heterologous expression In vitro assay
References	doi:10.1021/jacs.1c10201 doi:10.1002/anie.202113189

Example 1

Metadata	Description: oxidation of lysine to nitronorleucine Intermediate: False
Substrate
Product 1

Enzyme Information

Accession ID	MITE0000187
Entry Status	Status: active
Enzyme Name	HrmI
Enzyme Description	heme oxygenase-like dinuclear iron enzyme
Database References	UniProtKB: F8S6W0 NCBI GenPept: AEH41787.1 MIBiG: BGC0000374
Cofactors	Organic Heme Inorganic Fe
References	doi:10.1021/jacs.1c10201 doi:10.1002/anie.202113189
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-11-22)

Contributor(s)	0000-0001-6660-2715
Reviewer(s)	0000-0002-9747-3423
Comment	"Reviewer 1 checked for factual correctness of submission, database ID crosslinks and references."

Version 2 (2025-07-25)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609
Comment	"Added cofactor information"