Minimum Information about a Tailoring Enzyme Repository

MITE0000223

MITE0000224

MITE0000225

Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	Prenylation and Methyl esterification at free N- and C-termini of linear peptides
Tailoring	Methylation Prenylation
Database References	No database crosslinks available
Evidence	Inference from genomic data and chemical structure In vitro assay
References	doi:10.1021/jacs.6b12872

Example 1

Metadata	Description: Prenylation and Methyl esterification at free N- and C-termini of minimal substrate from the biosynthesis of aeruginosamide B Intermediate: True
Substrate 1
Product 1

Enzyme Information

Accession ID	MITE0000224
Entry Status	Status: active
Enzyme Name	AgeMTPT
Enzyme Description	Bifunctional prenyltransferase/methyltransferase
Database References	UniParc: UPI000261A9F7 NCBI GenPept: CCH92966.1 MIBiG: BGC0000483
References	doi:10.1016/j.chembiol.2013.06.015 doi:10.1021/jacs.6b12872
Comment	Prenylation and methyl-esterification at free N- and C-termini of linear peptides. Protein is annotated as AgeF1 in the original publication.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2025-11-23)

Contributor(s)	0000-0002-8834-593X
Reviewer(s)	0000-0002-8323-5416
Comment	"New entry. Updated former protein name (AgeF1). Updated citations."