MITE0000178

MITE0000179

MITE0000180

Reaction Information

Number of Known Reactions: 2

Reaction 1

Description	Hydroxylation
Tailoring	Hydroxylation
Database References	No database crosslinks available
Evidence	Heterologous expression
References	doi:10.1038/s41467-017-01659-1 doi:10.1002/cbic.201700434

Example 1

Metadata	Description: Conversion of premutilin to 11-hydroxypremutilin Intermediate: True
Substrate
Product 1

Reaction 2

Description	Hydroxylation
Tailoring	Hydroxylation
Database References	No database crosslinks available
Evidence	Heterologous expression
References	doi:10.1039/d2sc06638f

Example 1

Metadata	Description: Conversion of 3-hydroxypremutilin to 3,11-hydroxypremutilin Intermediate: True
Substrate
Product 1

Enzyme Information

Accession ID	MITE0000179
Entry Status	Status: active
Enzyme Name	Ple5
Enzyme Description	Cytochrome P450
Database References	UniProtKB: A0A6S6QPY4 NCBI GenPept: BCI98773.1 MIBiG: BGC0002181
References	doi:10.1038/s41467-017-01659-1 doi:10.1002/cbic.201700434 doi:10.1038/srep25202 doi:10.1039/d2sc06638f
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-11-14)

Contributor(s)	0000-0001-6585-0696
Reviewer(s)	0000-0001-6534-6609
Comment	"New entry. Reviewer 1 added descriptions to example reactions."