MITE0000203

MITE0000204

MITE0000205

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description AoL1 is an SDR responsible for converting 8-hydroxy aristolochene to 8-oxo-aristolochene
Tailoring
  • Oxidation
Database References No database crosslinks available
Evidence
  • Inference from genomic data and chemical structure
  • Heterologous expression
References
Example 1
Metadata
  • Description: Oxidation of 8-hydroxy group to 8-oxo, resulting in 8-oxo-aristolochene
  • Intermediate: True
Substrate substrate SMILES
Product 1 product SMILES
Example 2
Metadata
  • Description: Oxidation of 2,8-dihydroxy aristolochene to 2-hydroxy,8-oxo-aristolochene
  • Intermediate: True
Substrate substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000204
Entry StatusStatus: active
Enzyme NameAoL1
Enzyme DescriptionShort-chain dehydrogenase/reductase (SDR)
Database References
References
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2025-04-15)

Contributor(s)
Reviewer(s)
Comment "New entry. Reviewer 1 refined reaction SMARTS substrate specificity, added stereochemistry information, and added additional example."