MITE0000126

Reaction Information

Number of Known Reactions: 2

Reaction 1
reaction SMARTS
Description Bromination of L-tryptophan, leading to 5-bromotryptophan
Tailoring
  • Halogenation
Database References No database crosslinks available
Evidence
  • In vitro assay
References
Example 1
Metadata
  • Description: No description available
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES
Reaction 2
reaction SMARTS
Description Bromination of 5-bromotryptophan, leading to 5,7-bromotryptophan
Tailoring
  • Halogenation
Database References No database crosslinks available
Evidence
  • In vitro assay
References
Example 1
Metadata
  • Description: No description available
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000126
Entry StatusStatus: active
Enzyme NameAetF
Enzyme DescriptionFlavin-dependent halogenase
Database References
Cofactors
  • Organic
    • FAD
References
CommentCapable of iodinating and brominating arenes and olefins
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)
Reviewer(s)
Comment "Initial entry. Reviewer 1 determined the entry as unfixable (multiple reactions). Reviewer 2 broke up multi-reaction into two distinct ones."

Version 2 (2025-07-25)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "Added cofactor information"