MITE0000053

MITE0000054

MITE0000055

Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Flavin-dependent tryptophan-5-halogenase catalyzed halogenation reaction of deschloro-microbisporicin A2
Tailoring
  • Halogenation
Database References No database crosslinks available
Evidence
  • Heterologous expression
References
Example 1
Metadata
  • Description: Chlorination of deschloro-microbisporicin A2, leading to mature product.
  • Intermediate: False
Substrate substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000054
Entry StatusStatus: active
Enzyme NameMibH
Enzyme DescriptionFlavin-dependent halogenase
Database References
Cofactors
  • Organic
    • FAD
References
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)
Reviewer(s)
Comment "Initial entry. Reworked reaction SMARTS to have proper numbering. Reviewer "

Version 2 (2025-07-25)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "Added cofactor information"

Auxiliary Enzyme #1

Enzyme Name MibS
Description Flavin reductase providing FADH2 supply for chlorination
Database References