Minimum Information about a Tailoring Enzyme Repository

MITE0000117

MITE0000118

MITE0000119

Reaction Information

Number of Known Reactions: 1

Reaction 1

Description	reduction of exocxclic double bond in dehydroacaterin to acaterin
Tailoring	Reduction
Database References	No database crosslinks available
Evidence	Heterologous expression In vitro assay
References	doi:10.1002/anie.201914154 doi:10.1016/j.bmc.2006.05.039

Example 1

Metadata	Description: reduction of 4,5-didehydroacaterin to acaterin Intermediate: False
Substrate
Product 1

Enzyme Information

Accession ID	MITE0000118
Entry Status	Status: active
Enzyme Name	AcaR
Enzyme Description	NADPH-dependent oxidoreductase
Database References	UniProtKB: A0A5C4KWK7 NCBI GenPept: TNB95040.1 MIBiG: BGC0002076
Cofactors	Organic NADP
References	doi:10.1002/anie.201914154 doi:10.1016/j.bmc.2006.05.039
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2024-07-30)

Contributor(s)	0000-0002-4977-2541 0000-0002-9747-3423 Anonymous MITE contributor
Reviewer(s)	0000-0001-6660-2715 0000-0001-6534-6609
Comment	"Initial entry. Reviewer 1 added reaction description. Reviewer 2 replaced reaction SMILES to reaction SMARTS"

Version 2 (2025-07-25)

Contributor(s)	Anonymous MITE contributor
Reviewer(s)	0000-0001-6534-6609
Comment	"Added cofactor information"