MITE0000127

MITE0000128

MITE0000129

Reaction Information

Number of Known Reactions: 2

Reaction 1
reaction SMARTS
Description FADH2-dependent halogenase in the biosynthesis of chloroalbofungin
Tailoring
  • Halogenation
Database References No database crosslinks available
Evidence
  • Knock-out studies
References
Example 1
Metadata
  • Description: Chlorinates albofungin to chloralbofungin
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES
Reaction 2
reaction SMARTS
Description FADH2-dependent halogenase in the biosynthesis of bromoalbofungin variants
Tailoring
  • Halogenation
Database References No database crosslinks available
Evidence
  • Knock-out studies
References
Example 1
Metadata
  • Description: Brominates albofungin to bromalbofungin
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000128
Entry StatusStatus: active
Enzyme NameOrfA
Enzyme DescriptionHalogenase
Database References
Cofactors
  • Organic
    • FAD
References
Enzyme Visualization (AlphaFold-predicted) UniProt ID not available - could not render visualization

Version 1 (2024-07-30)

Contributor(s)
Reviewer(s)
Comment "Initial entry. Reviewer 1 fixed general aromaticity. Reviewer 2 added bromination reaction variant. Reviewer 3 improved descriptions."

Version 2 (2025-07-25)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "Added cofactor information"