MITE0000282
MITE0000283
MITE0000284
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Conversion of a 10,11-epoxide polyene intermediate into a tetrahydrofuran (2,5-dihydrofuran) derivative.
Tailoring
  • Cyclization
  • Ring expansion
Database References
Evidence
  • Heterologous expression
  • In vitro assay
  • Knock-out studies
References
Example 1
Metadata
  • Description: Transformation of epoxide to intermediate 2,5-dihydrofuran.
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000283
Entry StatusStatus: active
Enzyme NameDovD
Enzyme DescriptionEpoxide expandase (Cyclase)
Database References
References
CommentCatalyzes the regioselective rearrangement of the 10,11-epoxide into a 2,5-dihydrofuran ring via ring expansion.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-04-04)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "New entry."