MITE0000281
MITE0000282
MITE0000283
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Regioselective epoxidation of the 2,5-dihydrofuran moiety.
Tailoring
  • Monooxygenation
  • Oxidation
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • In vitro assay
  • Knock-out studies
References
Example 1
Metadata
  • Description: Final conversion of 2,5-dihydrofuran to epoxytetrahydrofuran
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000282
Entry StatusStatus: active
Enzyme NameDovE
Enzyme DescriptionCytochrome P450
Database References
Cofactors
  • Organic
    • Heme
    • NADP
  • Inorganic
    • Fe
References
CommentCatalyzes the final tailoring step: a second regioselective epoxidation on the 2,5-dihydrofuran ring to yield the terminal epoxytetrahydrofuran system.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-04-04)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "New entry."