MITE0000280
MITE0000281
MITE0000282
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Oxidative nitration of tyrosine using NO
Tailoring
  • Monooxygenation
Database References No database crosslinks available
Evidence
  • Inference from genomic data and chemical structure
  • In vitro assay
  • Knock-out studies
  • Site-directed mutagenesis
References
Example 1
Metadata
  • Description: Oxidative nitration of tyrosine using NO
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000281
Entry StatusStatus: active
Enzyme NameRufO
Enzyme DescriptionCytochrome P450
Database References
Cofactors
  • Inorganic
    • Fe
References
CommentOxidative nitration of tyrosine. MITE0000184 also describes RufO but enzyme AA sequences are only 97% identical.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-04-14)

Contributor(s)
Reviewer(s)
Comment "New entry. Reviewer 2 removed MIBiG reference since it referes to a different genome."

Auxiliary Enzyme #1

Enzyme Name RufN
Description Nitric oxide synthase
Database References