MITE0000283
MITE0000284
MITE0000285
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Regioselective epoxidation at the C10–C11 position of the deoxyverrucosidin polyene backbone.
Tailoring
  • Monooxygenation
  • Oxidation
Database References
Evidence
  • Heterologous expression
  • In vitro assay
  • Knock-out studies
References
Example 1
Metadata
  • Description: Epoxidation of the octaketide alpha-pyrone precursor to form the 10,11-epoxide intermediate.
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000284
Entry StatusStatus: active
Enzyme NameDovC
Enzyme DescriptionFlavin-containing monooxygenase (FMO)
Database References
Cofactors
  • Organic
    • FAD
    • NADP
  • Inorganic
    • Zn
References
CommentCatalyzes the first step of the tailoring cascade by performing regioselective epoxidation of the polyene chain.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-04-04)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "New entry."