MITE0000258
MITE0000259
MITE0000260
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Dehydrogenation of thiazolines to thiazoles in nosiheptide pathway. Current data indicates that full leader peptide is required for substrate recognition.
Tailoring
  • Dehydrogenation
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • Knock-out studies
References
Example 1
Metadata
  • Description: Thiazole-formation on modified NosM precursor peptide in nosiheptide biosynthetic pathway.
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000259
Entry StatusStatus: active
Enzyme NameNosF
Enzyme DescriptionDehydrogenase
Database References
References
CommentInteracts with NosGH in the formation of thiazole moieties in the nosiheptide biosynthetic pathway.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2025-12-30)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "New entry."

Auxiliary Enzyme #1

Enzyme Name NosG
Description E1-YcaO didomain protein
Database References

Auxiliary Enzyme #2

Enzyme Name NosH
Description Ocin-ThiF-like protein
Database References