MITE0000255
MITE0000256
MITE0000257
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Completion of 19-membered side ring system in nascent nosiheptide by C1 unit introduction and conjugation with Glu.
Tailoring
  • Cyclization
  • Methylation
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • In vitro assay
  • Knock-out studies
References
Example 1
Metadata
  • Description: Modifies the nascent nosiheptide precursor peptide NosM.
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000256
Entry StatusStatus: active
Enzyme NameNosN
Enzyme DescriptionRadical SAM enzyme
Database References
Cofactors
  • Organic
    • SAM
  • Inorganic
    • FeS
References
CommentCurrent knowledge indicates that the full leader peptide is required for substrate recognition by the enzyme.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2025-12-30)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "New entry."