MITE0000251
MITE0000252
MITE0000253
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description NosB hydroxylates the gamma-position of Glu6 in the nosiheptide biosynthetic pathway.
Tailoring
  • Hydroxylation
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • In vitro assay
  • Knock-out studies
References
Example 1
Metadata
  • Description: Final step in nosiheptide biosynthetic pathway, leading to mature nosiheptide
  • Intermediate: False
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000252
Entry StatusStatus: active
Enzyme NameNosB
Enzyme DescriptionCytochrome P450
Database References
Cofactors
  • Organic
    • Heme
  • Inorganic
    • Fe
References
CommentPart of the NosABC hydroxylation cascade, leading to mature nosiheptide.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2025-12-31)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "New entry."