MITE0000250
MITE0000251
MITE0000252
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Biaryl formation between Trp-C5 and Trp-N1 at the WxW motif; enzyme has promiscuous substrate specificity.
Tailoring
  • Biaryl bond formation
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • In vitro assay
  • Site-directed mutagenesis
References
Example 1
Metadata
  • Description: KwwA precursor peptide sequence MAAVLHRILNRKPARNWFWV
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000251
Entry StatusStatus: active
Enzyme NameKwwB
Enzyme DescriptionCytochrome P450
Database References
Cofactors
  • Organic
    • Heme
References
CommentUniProt identifier found via RefSeq accession WP_280689238.1
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2025-12-29)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "New entry. Reviewer fixed description."