MITE0000249
MITE0000250
MITE0000251
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Macrocyclization of DynB precursor peptide. Available information indicates that full leader peptide is required for substrate recognition.
Tailoring
  • Cyclization
Database References No database crosslinks available
Evidence
  • Heterologous expression
  • In vitro assay
References
Example 1
Metadata
  • Description: Macrocyclization of DynB precursor peptide into macrocyclized intermediate before cleavage to mature dynobactin A.
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000250
Entry StatusStatus: active
Enzyme NameDynA
Enzyme DescriptionRadical SAM enzyme
Database References
Cofactors
  • Organic
    • SAM
  • Inorganic
    • FeS
References
CommentCleavage of precursor peptide to mature dynobactin A by an unclustered (likely generic) protease.
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2025-12-29)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "New entry."