Reaction 1

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• Reaction Information

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Description	FasV catalyzes five successive chlorinations in the biosynthesis of naphthacemycin B13.
Tailoring	Halogenation
Database References	No database crosslinks available
Evidence	In vitro assay Site-directed mutagenesis
References	doi:10.1002/anie.202418843

Example 1

Metadata	Description: FasV, a flavin-dependent halogenase (FDH) that catalyzes five successive chlorinations in the biosynthesis of the naphthacene-containing aromatic polyketide naphthacemycin. This multiple halogenation reaction was elucidated to occur in an orderly fashion, as evidenced by enzyme kinetics, time-course assays, and computational simulations. Intermediate: False
Substrate 1	Copy SMILES
Product 1	Copy SMILES