MITE0000299
MITE0000300
MITE0000301
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Reaction Information

Number of Known Reactions: 3

Reaction 1
reaction SMARTS
Description Hydroxylation of Phe8 and Phe10 residues in PbsA3 precursor peptide
Tailoring
  • Hydroxylation
Database References No database crosslinks available
Evidence
  • Heterologous expression
References
Example 1
Metadata
  • Description: Hydroxylation of Phe8 and Phe10 residues in PbsA3 precursor peptide
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES
Reaction 2
reaction SMARTS
Description Hydroxylation of Phe10 in F8A variant of PbsA3
Tailoring
  • Hydroxylation
Database References No database crosslinks available
Evidence
  • Heterologous expression
References
Example 1
Metadata
  • Description: Hydroxylation of Phe10 in F8A variant of PbsA3
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES
Reaction 3
reaction SMARTS
Description Hydroxylation of Phe8 in F10A variant of PbsA3
Tailoring
  • Hydroxylation
Database References No database crosslinks available
Evidence
  • Heterologous expression
References
Example 1
Metadata
  • Description: Hydroxylation of Phe8 in F10A variant of PbsA3
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000300
Entry StatusStatus: active
Enzyme NamePbsC
Enzyme DescriptionMultinuclear nonheme Fe-dependent oxidative enzyme
Database References
Cofactors
  • Inorganic
    • Fe
References
CommentPbsCD is responsible for the ortho-hydroxylation of phenylalanine residue in PbsA1-4 precursor peptides analogue to biphenomycin
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-03-26)

Contributor(s)
Reviewer(s)
Comment "New entry. Added new MNIO enzyme PbsC (+PbsD partner). Reviewer 2 replaced retired UniProtKB IDs with UniParc Ids."

Auxiliary Enzyme #1

Enzyme Name PbsD
Description RRE-containing partner protein
Database References