Reaction 1

• Reaction SMARTS
• Reaction Information

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Description	3-methyl-2-indolic acid (MIA) synthase involved in nosiheptide biosynthesis
Tailoring	Carboxylation Deamination Decarboxylation
Database References	No database crosslinks available
Evidence	In vitro assay Knock-out studies Site-directed mutagenesis
References	doi:10.1038/nchembio.512

Example 1

Metadata	Description: Removal of the Ca-N unit of L-tryptophan and shift of carboxylate to the indole ring. Intermediate: True
Substrate 1	Copy SMILES
Product 1	Copy SMILES