MITE0000235
MITE0000236
MITE0000237
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Reaction Information

Number of Known Reactions: 1

Reaction 1
reaction SMARTS
Description Hydroxylates intermediate in beta-ethynylserine pathway, showing high substrate-specificity.
Tailoring
  • Hydroxylation
Database References
Evidence
  • Heterologous expression
  • In vitro assay
  • Site-directed mutagenesis
References
Example 1
Metadata
  • Description: Converts L-gamma-glutamyl-L-propargylglycine to L-gamma-glutamyl-(3R)-L-beta-ethynylserine in the beta-ethynylserine pathway
  • Intermediate: True
Substrate 1 substrate SMILES
Product 1 product SMILES

Enzyme Information

Accession IDMITE0000236
Entry StatusStatus: active
Enzyme NameBesE
Enzyme DescriptionHydroxylase
Database References
Cofactors
  • Organic
    • a-Ketoglutaric acid
  • Inorganic
    • Fe
References
CommentNonheme Iron(II) a-Ketoglutarate-Dependent dioxygenase
Enzyme Visualization (AlphaFold-predicted)

Version 1 (2026-01-29)

Contributor(s)
  • Anonymous MITE contributor
Reviewer(s)
Comment "New entry. Reviewer fixed typos."