{
    "accession": "MITE0000163",
    "status": "active",
    "changelog": [
        {
            "version": "1",
            "date": "2024-07-30",
            "contributors": [
                "AAAAAAAAAAAAAAAAAAAAAAAA"
            ],
            "reviewers": [
                "0000-0002-8323-5416"
            ],
            "comment": "Initial entry. Reviewer 1 checked crosslinks and factual correctness, corrected GenePeptID to UPG58737.1, added reaction description."
        }
    ],
    "enzyme": {
        "name": "PhoH",
        "description": "Decarboxylase",
        "references": [
            "doi:10.1021/acs.orglett.2c01050"
        ],
        "databaseIds": {
            "uniprot": "UPI0020648AC1",
            "genpept": "UPG58737.1",
            "mibig": "BGC0003093"
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Decarboxylation"
            ],
            "description": "Decarboxylase responsible for the conversion of atrochrysone carboxylic acid to atrochrysone.",
            "reactionSMARTS": "[#6:23][C:22]1([#8:1])[#6:21]-[c:20]2[c:19][c:18]3[c:17][c:16](-[#8:2])[c:15][c:14](-[#8:3])[c:13]3[c:12](-[#8:4])[c:11]2-[#6:10](=[O:9])-[#6:8]1-[#6:7](-[#8-:5])=[O:6]>>[#6:23][C:22]1([#8:1])[#6:8]-[#6:10](=[O:9])-[c:11]2[c:12](-[#8:4])[c:13]3[c:14](-[#8:3])[c:15][c:16](-[#8:2])[c:17][c:18]3[c:19][c:20]2-[#6:21]1",
            "reactions": [
                {
                    "substrate": "CC1(O)Cc2cc3cc(O)cc(O)c3c(O)c2C(=O)C1C(=O)[O-]",
                    "products": [
                        "CC1(O)CC(=O)c2c(cc3cc(O)cc(O)c3c2O)C1"
                    ],
                    "isIntermediate": true
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Heterologous expression"
                ],
                "references": [
                    "doi:10.1021/acs.orglett.2c01050"
                ]
            }
        }
    ]
}